Sentinel Lymph Node Biopsy Predictive Value in Endometrial Cancer of Low and Intermediate Risk

  • STATUS
    Recruiting
  • End date
    Jul 7, 2023
  • participants needed
    100
  • sponsor
    Moscow City Oncology Hospital No. 62
Updated on 24 October 2021
cancer
hysterectomy
indocyanine green
metastasis
lymphadenectomy
adjuvant therapy
laparoscopy
adenocarcinoma
endometrial adenocarcinoma

Summary

Lymphadenectomy performed for endometrial cancer influences the decision on adjuvant therapy. The aim of this study is to evaluate the rate of change in postoperative treatment based on the result of sentinel lymph node biopsy (SLNB).

Details
Condition Hysterectomy, Endometrial Carcinoma, Uterine Cancer, Sentinel Lymph Node, Endometrial Adenocarcinoma, Sentinel Node, Laparoscopic Hysterectomy, Endometrial Endometrioid Adenocarcinoma, Endometrial Cancer Stage I, Endometrial Cancer Stage II, hysterectomies, stage ii endometrial cancer, endometrioid adenocarcinoma of the endometrium
Treatment Laparoscopic hysterectomy with sentinel lymph node biopsy
Clinical Study IdentifierNCT04972682
SponsorMoscow City Oncology Hospital No. 62
Last Modified on24 October 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Age 18
Histologically verified low-grade endometrial adenocarcinoma of the endometrium (G1-G2)
Stage IA (FIGO 2009) according to MRI (CT, ultrasound)
Stage IB and II (FIGO 2009) when lymphadenectomy is contraindicated
No contraindications for surgery
Signed informed consent

Exclusion Criteria

Age <18
Signs of tumor spread outside the corpus uteri
No signs of tumor invasion into the myometrium
High-grade tumor (G3)
Bokhman type 2 tumor (serous adenocarcinoma, clear cell adenocarcinoma, carcinosarcoma, endometrial stromal sarcoma, etc.)
Preoperative treatment of endometrial cancer (radiation therapy, chemotherapy or hormone therapy)
Prior pelvic or retroperitoneal lymphadenectomy
Prior surgery on the uterus and uterine appendages (except for cesarean section, tubectomy, ovariectomy, ovarian resection, ovarian biopsy, ovarian cauterization)
Surgical treatment is contraindicated
Allergy to iodine-containing drugs
No signed informed consent
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note