Phase 1 Study To Assess the Safety and Tolerability of Human Embryonic Stem Cell-Derived Midbrain Dopamine Neuron Cell Therapy (MSK-DA01) For Advanced Parkinson's Disease

    Not Recruiting
  • sponsor
Updated on 8 August 2022


Dopamine neurons made from stem cells are injected into the brain under general anesthesia. Subjects then take medicines to partially suppress their immune system (aimed to prevent the body from rejecting the cells) for 1 year. All subjects receive the treatment (i.e. there is no placebo group in this study).  Safety, tolerability, evidence of cell survival (using scans of the brain), and the effect on Parkinson's disease symptoms are assessed for 2 years post-transplant


Condition Cell Therapy, dopamine, stem cells, surgery, stem cell, neurosurgery, Parkinson's disease, neurology
Clinical Study IdentifierTX278586
Last Modified on8 August 2022

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