Efficacy of Drinking Water During Capsule Endoscopy

  • End date
    Sep 30, 2023
  • participants needed
  • sponsor
    Shandong University
Updated on 31 July 2021


The aim of this study was to determine whether drinking water improves the complete examination rate (CER) of the small bowel by reducing the gastric transit time (GTT) of the capsule.


Capsule endoscopy has been a significant technologic advancement that has allowed the direct examination of mucosa throughout the entire small intestine in a noninvasive fashion; and it has become the primary technique for imaging the small bowel. However, as imaging time is limited to about 8 hours, a prolonged transit of the capsule endoscope in the stomach may result in an incomplete small bowel transit (i.e. failure of the capsule to reach the cecum). Failure to reach the cecum is reported to occur in approximately 20 % of all procedures. Delayed GTT may be responsible for the failure of capsule endoscopy to visualize the distal portions of the small bowel, and potentially may result in the inability to identify small-bowel pathology in these areas. Previous study showed that drinking water might improve CER of capsule endoscopy. The aim of this study was to assess the effect of drinking water on the GTT and complete examination rate (CER) of capsule endoscopy.

Condition Capsule Endoscopy
Treatment Control group, drinking water group
Clinical Study IdentifierNCT04970277
SponsorShandong University
Last Modified on31 July 2021


Yes No Not Sure

Inclusion Criteria

Patients aged 18-85 years undergoing capsule endoscopy

Exclusion Criteria

Patients with suspected intestinal obstruction, intestinal diverticulum, stricture or fistula
previous gastric or small-bowel surgery
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