Screening for Alcohol-related Cognitive Impairments in Cirrhotic Patients

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  • sponsor
    Centre Hospitalier Universitaire, Amiens
Updated on 17 September 2021
biopsy of liver
alcoholic cirrhosis


80% of patients with alcohol use disorders (AUD) present cognitive impairments, such as memory and executive functions. These disorders may have repercussions in addiction treatment by altering the patient's adherence to care. The level of impairment is dependent on the onset of addiction, and also the duration of abstinence.

A complete neuropsychological evaluation is necessary to highlight cognitive impairments. In practice, the evaluation of these disorders by practitioners, is done with the help of tools of screening like the MoCa (Montreal cognitive assesment) and the BEARNI (Brief evaluation of alcohol related neuropsychological impairment).

However, none of these tools have been evaluated in patients with alcoholic cirrhosis. Indeed, some studies have suggested that liver disorders including cirrhosis may be a factor aggravating cognitive disorders.

The purpose of this study is to evaluate the ability of the BEARNI tool to detect alcohol-related cognitive problems in patients with alcohol-related cirrhosis.

Condition hepatic diseases, Alcohol abuse, Dependency, Fibrosis, alcoholism, Hepatic Fibrosis, hepatic cirrhosis, Cognitive Impairment, liver diseases, neurocognitive disturbance, chronic alcoholism, Liver Disorders, Cognitive Impairments, hepatopathy, LIVER DISEASE, dependence on, Alcohol Dependence, Cognitive Dysfunction, hepatic disease, alcohol dependence syndrome, Cirrhosis, liver cirrhosis, Alcohol Use Disorder, hepatic pathology, Liver Disease
Treatment Questionnaire
Clinical Study IdentifierNCT04490330
SponsorCentre Hospitalier Universitaire, Amiens
Last Modified on17 September 2021


Yes No Not Sure

Inclusion Criteria

Patient with cirrhosis
patients with cirrhosis diagnosed by clinical examination
patients with cirrhosis diagnosed by biological and / or morphological and / or noninvasive tests and / or liver biopsy

Exclusion Criteria

hepatitis encephalopathy less than 6 months old
complicated cirrhosis with hepatocellular carcinoma
Acute alcoholic hepatitis
viral cirrhosis
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