Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity

  • STATUS
    Recruiting
  • End date
    Dec 14, 2022
  • participants needed
    26
  • sponsor
    Oklahoma State University Center for Health Sciences
Updated on 14 May 2022
Accepts healthy volunteers

Summary

This study will examine the effect of a real-time functional magnetic resonance imaging (fMRI) dyadic neurofeedback protocol with mothers and their adolescent daughters. Mothers will view a moving bar showing their daughters' brain activity on a computer screen while talking to their daughters.

Description

The current study will determine the effects of a real-time functional magnetic resonance imaging dyadic neurofeedback (rtfMRI-DNF) protocol that will train mothers with a history of adverse childhood experiences (ACEs) to regulate adolescents' activation in the anterior insular cortex (aIC) - a key brain region for ER. The proposed study will test the efficacy of this protocol to promote healthy ER-related neurodevelopment in adolescents with a maternal history of adversity. The proposed study will use DNF to provide neurofeedback from the adolescent's aIC to the parent as the parent and adolescent engage in an emotion discussion task together. Parents and adolescents (n=10 dyads) will communicate via microphones and noise-canceling headphones while the adolescent is undergoing fMRI scanning. Specific aims of the current study are: (1) to determine the brain response to aIC DNF adolescents, and (2) to determine effects of DNF on parenting behaviors. This study is significant because engaging with parents in DNF can promote positive ER development in adolescents at risk due to the intergenerational effects of ACEs.

Details
Condition Emotional Dysfunction, Early Life Stress
Treatment Real-time fMRI dyadic neurofeedback
Clinical Study IdentifierNCT04964726
SponsorOklahoma State University Center for Health Sciences
Last Modified on14 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

All participants inclusion criteria
Biological female
Sufficient English fluency to complete tasks
Co-residing at least 4 days per week
Inclusion criteria for adult participants
Primary caregiver for more than 50% of child's lifespan
History of at least two adverse childhood experiences
Biological parent of adolescent participant
Inclusion criteria for adolescents
Eligible for fMRI
Right-handed
Body mass index between 16 and 40 (inclusive)
Age 14-17 years

Exclusion Criteria

Exclusion criteria for all participants
Current psychiatric diagnosis
Exclusion criteria for adolescent participants
Neurodevelopmental delay
History of psychiatric disorder
Medications influencing fMRI
Medical conditions influencing fMRI
Clear my responses

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