Closed-loop Oxygen Control for High Flow Nasal Therapy

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    Hospital Universitari Vall d'Hebron Research Institute
Updated on 15 September 2021


In patients with acute hypoxemic respiratory failure (AHRF), High Flow Nasal Therapy (HFNT) improves oxygenation, tolerance, and decrease work of breathing as compared to standard oxygen therapy by facemask. Current guidelines recommend adjusting oxygen flow rates to keep the oxygen saturation measured by pulse oximetry (SpO2) in the target range and avoid hypoxemia and hyperoxemia. The hypothesis of the study is that closed loop oxygen control increases the time spent within clinically targeted SpO2 ranges and decreases the time spent outside clinical target SpO2 ranges as compared to manual oxygen control in ICU patients treated with HFNT.

Condition Hypoxia, Pulmonary insufficiency, Respiratory Failure, Oxygen therapy, Acute Respiratory Failure, High Flow Nasal Cannula, Hyperoxemia, respiratory insufficiency, pulmonary regurgitation, pulmonic valve insufficiency, respiratory impairment
Treatment No intervention, Oxygen close-loop
Clinical Study IdentifierNCT04965844
SponsorHospital Universitari Vall d'Hebron Research Institute
Last Modified on15 September 2021

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