Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

  • End date
    Jun 1, 2022
  • participants needed
  • sponsor
    University of California, Los Angeles
Updated on 22 July 2021
ophthalmic solution
brimonidine tartrate ophthalmic solution


To evaluate glaucoma patients' response to treatment with Xiidra, an FDA-approved drug for ocular surface discomfort, which will be prescribed as standard of care treatment.


To assess glaucoma patients' response to treatment with Xiidra (Lifitegrast ophthalmic solution) 5% for ocular surface discomfort caused, in part, by topical glaucoma antihypertensive medications.

Condition Ocular Hypertension, Glaucoma, Ocular Surface Disease
Treatment Xiidra (Lifitegrast ophthalmic solution) 5%
Clinical Study IdentifierNCT04354545
SponsorUniversity of California, Los Angeles
Last Modified on22 July 2021


Yes No Not Sure

Inclusion Criteria

Currently using one or more topical glaucoma antihypertensives
Self-described symptoms of ocular surface discomfort
Xiidra is being prescribed as part of the subject's standard care

Exclusion Criteria

History of glaucoma filtration surgery, history of ocular surface surgery (pterygium, conjunctivoplasty, etc.)
current use of topical cyclosporine
current use of topical steroids
incisional ocular surgery within 6 months
Clear my responses

How to participate?

Step 1 Connect with a site
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Preferred Language
Other Language
Please verify that you are not a bot.

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note