A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.
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- STATUS
- Recruiting
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- End date
- Sep 30, 2024
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- participants needed
- 318
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- sponsor
- Louis Bherer
Summary
The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.
Description
The proportion of older adults is on the rise in Canada, with the fastest growth recorded among those seventy years of age or older. The prevalence of cardiovascular risk factors (CVRF) such as diabetes, hypertension, and high cholesterol increases drastically with age. Individuals with CVRF often show impaired cognition, such as attention and memory deficits. In healthy older adults, exercise training and cognitive stimulation can help enhance cognitive performances. More precisely, combined intervention, including physical and cognitive training, has shown beneficial effects on cognition in older adults without cognitive impairment and with mild cognitive impairment. However, the effect of such programs on cognition in individuals with CVRF is not well documented. This project compares the effect of a physical exercise program, including aerobic and resistance training, alone or combined with cognitive training on cognitive performances and brain imaging outcomes in individuals with CVRF and healthy controls.
Details
| Condition | Aging, Senility, Cardiovascular Risk Factor |
|---|---|
| Treatment | Cognitive training, Stretching and toning, Aerobic and resistance exercises |
| Clinical Study Identifier | NCT04962061 |
| Sponsor | Louis Bherer |
| Last Modified on | 6 October 2021 |
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