Impact of Hospitalization on High-sensitivity Cardiac Troponin T Concentrations Depending on Disease Severity

  • End date
    Jul 21, 2023
  • participants needed
  • sponsor
    University of Leipzig
Updated on 21 July 2021


We aim to examine, whether hospitalization is associated with higher high-sensitivity cardiac troponin T (hs-cTnT) serum concentrations in patients without a cardiac disease.


High-sensitivity cardiac troponin T (hs-cTnT) values will be obtained in hospitalized patients a) without a diagnosed or suspected cardiac disease, and b) with an acute medical condition that is not commonly associated with an increase of hs-cTnT concentrations. As a reference, a second sampling of blood for an analysis of the hs-cTnT serum concentration will be obtained in the same patients after discharge (60 days after hospitalization).

Condition Non-cardiac Disease
Treatment Analysis of hs-cTnT serum concentration at hospitalization, Analysis of hs-cTnT serum concentration after discharge
Clinical Study IdentifierNCT04963400
SponsorUniversity of Leipzig
Last Modified on21 July 2021


Yes No Not Sure

Inclusion Criteria

hospitalization due to a non-cardiac disease
age 50 years

Exclusion Criteria

diagnosed or suspected cardiac disease
acute medical conditions commonly associated with a myocardial injury (e.g. circulatory shock, sepsis, pulmonary embolism, cerebral infarction, acute renal failure)
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