Seal, Stopping Eczema and Allergy Study
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- STATUS
- Recruiting
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- End date
- Jul 14, 2027
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- participants needed
- 875
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- sponsor
- Kari Christine Nadeau, MD, PhD
Summary
This is a randomized, controlled trial designed for children who are have already developed atopic dermatitis (AD or eczema) by 12 weeks of age. The aim is to compare the effect of proactive sequential skin care, including the twice-daily use of a tri-lipid skin barrier cream (Epiceram) or moisturizer and proactive use of fluticasone propionate cream, against reactive AD therapy, to reduce the occurrence and severity of AD in early infancy and thereby prevent food allergy (FA).
Description
This is a randomized, controlled, parallel design, open-label phase 2 clinical study to compare the efficacy of the two proactive treatment arms versus the reactive arm, for the prevention of atopic dermatitis in children at high risk of food allergy. We will recruit 875 infants who have signs of dry skin or atopic dermatitis between 0-12 weeks of life.
The aim is to compare the effect of proactive sequential skin care, including the twice-daily use of a tri-lipid skin barrier cream (Epiceram) or moisturizer and proactive use of fluticasone propionate cream, against reactive AD therapy, to reduce the occurrence and severity of AD in early infancy and thereby prevent food allergy (FA).
Details
| Condition | Eczema, Infantile, Eczema, Atopic Dermatitis Eczema, Atopic Dermatitis |
|---|---|
| Treatment | Standard of Care, Moisturizer, Tri-lipid skin barrier cream (Epiceram), Fluticasone propionate Cream 0.05% |
| Clinical Study Identifier | NCT03742414 |
| Sponsor | Kari Christine Nadeau, MD, PhD |
| Last Modified on | 14 July 2022 |
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