Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain

  • End date
    Mar 31, 2024
  • participants needed
  • sponsor
    University of Michigan
Updated on 13 October 2021
chronic pain
spinal cord
intractable pain
pain relieving
chronic pain management
sensory testing


Doctors sometimes treat chronic pain with devices that send mild electrical currents into the spinal cord. This type of treatment is referred to as neurostimulation. A common form of neurostimulation therapy is spinal cord stimulation (SCS). In this study, researchers want to learn more about how SCS affects pain processing and relieves pain. The researchers will examine multiple forms of SCS in chronic pain patients who are receiving SCS from their own doctors as part of their standard of care. During the study, participants will be asked to complete a variety of evaluations at certain time points.

Condition Pain, Pain (Pediatric), Chronic Pain, Post-Surgical Pain, chronic pains, Complex regional pain syndrome, neuropathic pain, Peripheral Neuropathy, Neuralgia, Failed Back Surgery Syndrome, Complex Regional Pain Syndrome- type 1 (CRPS-I)
Treatment Spinal cord stimulation
Clinical Study IdentifierNCT04732325
SponsorUniversity of Michigan
Last Modified on13 October 2021


Yes No Not Sure

Inclusion Criteria

Chronic intractable pain of the trunk and/or limbs
Undergoing SCS as part of standard clinical care for chronic pain management
Candidates will have been implanted with a commercial SCS device
Candidates who are 18 years or older and can speak, read, and understand English
Able to understand study procedures and to comply with them for the entire length of the study
Must be willing to participate in COVID-19 symptom screening and answer questions about COVID-19 diagnosis 1-3 days before a scheduled visit
Must be willing to wear a face-covering during all study visits

Exclusion Criteria

Subjects who are pregnant or nursing
Subjects with current, habitual, or previous use within the last 12 months of artificial nails, nail enhancements, or nail extensions that cover any portion of either thumbnail
Subjects who are unable or unwilling to cooperate with clinical testing
Subjects having any impairment, activity or situation that in the judgment of study personnel would prevent satisfactory completion of the study protocol
Inability or unwillingness of individual or legal guardian/representative to give written informed consent
Subjects who currently have or tested positive in the last 14 days for COVID-19, or are symptomatic for COVID-19
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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