Brain iron, amyloid, and Alzheimer's disease

  • End date
    Apr 30, 2025
Updated on 3 March 2022


The goal of this study is to determine how levels of iron in the brain can affect proteins associated with Alzheimer’s disease, including amyloid.


Participants will undergo 3 procedures, which may be done on the same day or separate days. These will include screening and cognitive testing (up to 2-3 hours, can be done remotely via Zoom), a 1-1.5 hour MRI scan (this will involve no radiation and no injection), and a blood draw. The 4th procedure, a lumbar puncture, will be optional; this entails putting a small needle in the lower back, below the level of the spinal cord, to take a small amount of spinal fluid.

Condition Alzheimer's Disease, Mild Cognitive Impairment, Healthy Volunteers
Clinical Study IdentifierTX276583
Last Modified on3 March 2022


How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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