Phase 1 study of BAY1905254 - An early clinical research study to evaluate a new drug called Bapotulimab (BAY1905254) in the expansion cohort in combination with Pembolizumab in Head and Neck cancer that has returned or is discovered to be metastatic and is expressing PDL1.

  • STATUS
    Not Recruiting
  • sponsor
    Bayer HealthCare
Updated on 18 August 2022
carcinoma
squamous cell carcinoma
pembrolizumab
primary tumor
metastatic head and neck cancer
metastatic head and neck squamous cell carcinoma

Summary

This study is being done to learn more about a new drug called Bapotulimab given in combination with Pembrolizumab.  The purpose of this study is to learn if this new combination of drugs is safe for the participants, how it affects the body and to try to find the best dose of the new drug to give to participants and to obtain a preliminary assessment of the tumor response efficacy in the recurrent or metastatic Head and Neck Cancer.

Description

For additional information: clinicaltrials.gov/ct2/show/NCT03666273

Details
Condition Pembrolizumab, Immunotherapy, Head and Neck Cancer, HNSCC, PD1, Immune checkpoint inhibitor, Bapotulimab, PDL1, ILDR2, head and neck cancer, Oncology, Head and Neck Cancer
Clinical Study IdentifierTX276581
SponsorBayer HealthCare
Last Modified on18 August 2022

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