A Study to Assess the Safety Tolerability Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of ION547

  • STATUS
    Recruiting
  • End date
    Jun 11, 2022
  • participants needed
    76
  • sponsor
    Ionis Pharmaceuticals, Inc.
Updated on 11 July 2021
Investigator
Ionis Pharmaceuticals
Primary Contact
BioPharma Services, Inc. (9.7 mi away) Contact

Summary

The purpose of this study is to evaluate the safety and tolerability of single and multiple doses of the antisense inhibitor ION547 administered subcutaneously (SC) in healthy participants.

Description

This is a Phase 1, double-blind, randomized, placebo-controlled, dose escalation study of ION547 in up to 76 participants. Participants will be randomized to receive single and multiple doses of ION547 or placebo SC. The maximum length of participation in the study will be approximately 34 weeks.

Details
Condition Healthy Volunteers
Treatment Placebo, ION547
Clinical Study IdentifierNCT04934891
SponsorIonis Pharmaceuticals, Inc.
Last Modified on11 July 2021

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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