Essential Oils Following IUD Insertion

  • End date
    Dec 25, 2023
  • participants needed
  • sponsor
    Aurora Health Care
Updated on 25 June 2021
iud insertion


This study will measure the effects of topical application of sweet marjoram essential oil + grapeseed oil with massage on uterine cramping/pain post-IUD insertion/placement.

The intention is to conduct a pilot study that could give a first look at the data to determine whether this line of research is worth pursuing with more time, effort, and resources. The results of this pilot study will provide adequate data (e.g., variance estimates) needed for obtaining reasonably reliable sample size estimates if larger studies are warranted in the future.


Patients will be consented and randomized to one of three methods by a member of the study team on the day of their IUD insertion. Several variables of interest will be collected via the electronic medical record and via questionnaire.

Condition Myalgia, Muscle Pain, Fetal Death, myalgias, Intrauterine Device, Muscle Soreness, fetal demise, intrauterine fetal demise, pain, muscle, intrauterine fetal death, muscle pains, muscular pain
Treatment Grapeseed Oil, Sweet Marjoram Essential Oil
Clinical Study IdentifierNCT04927741
SponsorAurora Health Care
Last Modified on25 June 2021


Yes No Not Sure

Inclusion Criteria

years of age or older at time of IUD insertion
English speaking
Subject has signed study-specific consent form
Subject has taken clinic recommended NSAID at least 30 minutes prior to IUD insertion

Exclusion Criteria

Subject is in post-partum period
Known allergies to sweet marjoram essential oil or grapeseed oil
Broken or irritated skin on lower abdomen
Diagnosis of IBS/IBD
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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