Assessing the Role of Inclined Positioning in Acute Respiratory Distress Syndrome Patients Recovery

  • STATUS
    Recruiting
  • End date
    Nov 22, 2022
  • participants needed
    40
  • sponsor
    Peter Morris
Updated on 22 June 2021
acute respiratory distress

Summary

The purpose of this study is to determine the effect of intermittent, nearly vertical, patient positioning in a specialized upright bed, on outcomes of mechanically ventilated patients with acute respiratory distress syndrome (ARDS) who are in the ICU.

Description

The purpose of this study is to determine the effect of intermittent, nearly vertical, patient positioning in a specialized upright bed, on outcomes of mechanically ventilated patients with acute respiratory distress syndrome (ARDS) who are in the ICU. This study is a prospective, non-blinded, feasibility, randomized study of ARDS patients, who will be randomized into two treatment groups. One treatment arm will deliver scheduled sessions of upright bed positioning (study intervention), while the other treatment arm receives routine bed position care (care provided exclusively with the bed in the supine position). ICU Practitioners know that positional changes improve clinical outcomes when turning patients from supine to prone (back to belly); however, other positional changes including upright positioning are far less studied. It is well known that in ARDS patients who become proned, an improvement in aeration occurs in the dorsal lung regions (prone positioning has been shown to reduce ARDS mortality). Thus the investigators predict that in this study, the upright positioning holds the potential to further recruit collapsed lung areas. Augmentation of aerated lung while in the upright position is expected to increase the highest value measured per ventilator day of the respiratory system compliance in the upright bed position arm, in a greater fashion than the highest value measured per ventilator day of daily total respiratory system compliance for the usual care arm.

Details
Condition ADULT RESPIRATORY DISTRESS SYNDROME
Treatment upright bed
Clinical Study IdentifierNCT04612608
SponsorPeter Morris
Last Modified on22 June 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Berlin criteria ARDS

Exclusion Criteria

ARDS greater than 72 hours
Neurologic disease known to prolong weaning
Pregnancy
Known diagnosis of pulmonary fibrosis
Implanted cardiac pacer/defibrillator
prisoner
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