Amyloid-beta PET Imaging With 18F-92 in Alzheimer's Disease
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- STATUS
- Recruiting
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- End date
- Jul 1, 2024
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- participants needed
- 50
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- sponsor
- First Affiliated Hospital of Fujian Medical University
Summary
Alzheimer's disease is a neurodegenerative disease. Numerous studies have reported that β-amyloid (Aβ) is an important marker for the diagnosis of AD. 18F-92 molecular probe is a novel molecularly targeted imaging agent, which can rapidly penetrate the blood-brain barrier and has high affinity and selectivity for Aβ protein. In this study, 18F-92 PET/CT was used to monitor the regional distribution and the degree of deposition in patients with Alzheimer's disease, and compared with clinical symptoms (neuropsychometry) to evaluate its application value in the diagnosis of AD.
Description
Healthy volunteers as well as patients meeting Alzheimer's criteria will be recruited for this study.
We will use PET/CT imaging technology to scan each participant's whole body or head and collect image data for analysis to evaluate the distribution and metabolism of 18F-92 in the subject's body. Time from drug injection to scan completion is approximately 1 hour.
Details
| Condition | Alzheimer's Disease |
|---|---|
| Treatment | 18F-92 |
| Clinical Study Identifier | NCT04926272 |
| Sponsor | First Affiliated Hospital of Fujian Medical University |
| Last Modified on | 24 January 2022 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
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