Comparation of CLASS Combined With Phacoemulsification and CLASS Alone in the Treatment of Primary Open Angle Glaucoma

  • STATUS
    Recruiting
  • End date
    Aug 20, 2023
  • participants needed
    80
  • sponsor
    Second Affiliated Hospital, School of Medicine, Zhejiang University
Updated on 20 June 2021
cataract
brimonidine tartrate ophthalmic solution
intraocular pressure
phacoemulsification
hypotensive
primary open angle glaucoma
hypotensive agents

Summary

To compare the effect of intraocular pressure control and the incidence of peripheral anterior synechia between CLASS combined with phacoemulsification and CLASS alone in the treatment of primary open-angle glaucoma

Description

Group A: CO2 Laser-Assisted Sclerectomy Surgery combined with phacoemulsification; Group B: simple CO2 Laser-Assisted Sclerectomy Surgery. The patients were followed up for 1 year. The incidence of peripheral anterior synechia and Intraocular pressure changes at 1 day, 1 week, 1 month, 2 months, 3 months, 6 months and 12 months were observed and compared between the two groups.

Details
Condition Pigmentary glaucoma, Open Angle Glaucoma
Treatment phacoemulsification;
Clinical Study IdentifierNCT04920227
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
Last Modified on20 June 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Primary open-angle glaucoma patients with cataract in our Ophthalmic Center
Topical use of hypotensive drugs in the treatment of poor or intolerable intraocular pressure control
The patients were aged from 50 to 80 years old, regardless of gender
Class operation and phacoemulsification were performed
Patients are able and willing to comply with the research guidance and may complete all visits required by the research
Informed consent has been signed

Exclusion Criteria

Allergic to any perioperative medication in this study
History of ocular trauma
Any previous intraocular surgery
Angle of the chamber was narrow by angle microscopy (Schaffer grade III and below)
Patients diagnosed as secondary glaucoma
Optic atrophy caused by other reasons
The serious complications such as posterior capsule rupture and choroidal hemorrhage occurred during the operation
Serious complications of eyes occurred after operation
The patient's history indicated that he had severe dysfunction of heart, lung, liver and kidney
Women in pregnancy, lactation or planned pregnancy
The researchers believe that the patient's condition may put the patient at significant risk, and may confuse the research results
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