Genome-based Management of Patients in Precision Medicine (Ge-Med) Towards a Genomic Health Program (GE-MED)

  • End date
    Jul 23, 2027
  • participants needed
  • sponsor
    University Hospital Tuebingen
Updated on 23 May 2022


The GE-MED APPROACH project will enroll patients (n = appr. 12.000) with unclear molecular cause of the disease, suspected genetic cause of the disease without detailed molecular analysis like Whole Exome Sequencing (WES).

The novelty of this study is to integrate genomic health concepts into immediate clinical care. To achieve these goals, a novel structure for the Triple P (3P) concept of personalized medicine (Personalized, Predictive, Preventive) integrated into a well-established health care system and associated with novel decentralized Disease Analysing Task Forces (DATF) will be implemented.

The overall goal of this study is to implement, for the first time, Whole Genome Sequencing (WGS) analysis as a first line diagnostic test for all clinical indications such as Rare Disease (RD )and familial cancer syndromes.

Condition Rare Diseases, Genetic Predisposition to Disease
Treatment WGS Diagnostic: Blood take for genetic diagnostic
Clinical Study IdentifierNCT04760522
SponsorUniversity Hospital Tuebingen
Last Modified on23 May 2022


Yes No Not Sure

Inclusion Criteria

Unclear molecular cause of the disease
Suspected genetic cause of the disease

Exclusion Criteria

Missing informed consent of the patient and if applicable the legal representative
Previously performed WES or panel analysis
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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