Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation Other Cellular Therapies and Marrow Toxic Injuries

  • End date
    Jul 20, 2025
  • participants needed
  • sponsor
    Center for International Blood and Marrow Transplant Research
Updated on 20 June 2021


The primary purpose of the Research Sample Repository is to make blood samples available for research studies related to histocompatibility and hematopoietic cell transplantation (HCT) or other cellular therapy.

Representatives of participating centers and investigators or research groups may request access to research samples contained in the Research Sample Repository for the purpose of conducting research including:

  • investigating molecular explanations for histocompatibility or clinical outcomes through analysis of genomic, epigenetic, or other biomolecular data
  • evaluating the factors that affect transplant or cellular therapy outcome
  • studying the distribution of HLA tissue types in different populations
  • studying the success of transplantation, cellular therapies or supportive care in the management of marrow toxic injuries
  • performing de-linked (anonymous) research


Research samples will be accepted from the following four categories:

  • Hematopoietic Cell or other Cellular Therapy Donors
  • Cord Blood Units
  • Hematopoietic Cell Transplantation or other Cellular Therapy Recipients
  • Patients with Marrow Toxic Injury

Condition Autologous Hematopoietic Stem Cell Transplantation, cellular therapy, Allogeneic Stem Cell Transplantation, cell therapy, Allogeneic Hematopoietic Cell Transplantation, Allogeneic Hematopoietic Stem Cell Transplantation, Marrow Toxic Injury, Autologous Stem Cell Transplantation
Clinical Study IdentifierNCT04920474
SponsorCenter for International Blood and Marrow Transplant Research
Last Modified on20 June 2021


How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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