Minimum Effective Volume for Selective Trunk Block

  • STATUS
    Recruiting
  • End date
    Jan 4, 2022
  • participants needed
    25
  • sponsor
    Chinese University of Hong Kong
Updated on 4 June 2021

Summary

The objective of this study is to identify the minimum effective dosage of a mixture of two local anaesthetic drugs called 'levobupivacaine' and 'lignocaine with epinephrine" used to produce an effective ultrasound guided selective trunk block for surgical anaesthesia of the upper limb.

Description

Ultrasound is widely used for brachial plexus block (BPB) and current evidence indicates that it is feasible to accurately identify majority of the main components of the brachial plexus above the clavicle, including the three trunks. Since majority of the innervation to the upper extremity, including the shoulder, arises from the three trunks (superior, middle and inferior) of the brachial plexus, so targeted injections of the individual trunks of the brachial plexus under ultrasound guidance will produce surgical anaesthesia of the entire upper extremity (C5-T1). Principal Investigator refers to this novel technique "selective trunk block" (SeTB) and the preliminary experience with SeTB for surgical anaesthesia of the entire upper extremity has been very encouraging. Currently there are no data describing an optimal dose or volume of local anaesthetic for SeTB. The aim of this study is to identify the minimum dosage of 1:1 mixture of 'levobupivacaine' and "lignocaine with epinephrine" required to produce effective surgical anaesthesia in at least 90% of patients presented for upper limb surgery.

Details
Condition Musculoskeletal Diseases or Conditions
Treatment a 1: 1 mixture of 2% lidocaine with 5ug/ml epinephrine and 0.5% levobupivacaine
Clinical Study IdentifierNCT04773405
SponsorChinese University of Hong Kong
Last Modified on4 June 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

American Society of Anesthesiologists (ASA) physical status I-III scheduled to undergo elective upper extremity surgery involving the proximal humerus to distal hand or surgery involving any combination of these regions

Exclusion Criteria

Patient refusal
pregnancy
skin infection at the site of block placement
history of allergy to local anaesthetic drugs
history of bleeding tendency or with evidence of coagulopathy
pre-existing neurological deficit
pre-existing neuromuscular disease
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