Azithromycin Reduction to Reach Elimination of Trachoma (ARRET)

  • End date
    Jan 31, 2027
  • participants needed
  • sponsor
    University of California, San Francisco
Updated on 20 August 2023
Accepts healthy volunteers


The investigators propose a randomized controlled trial of discontinuation versus continuation of annual mass azithromycin distribution in hypoendemic communities of Maradi, Niger. The investigators will randomize communities with up to 20% Trachomatous Inflammation

  • Follicular (TF) prevalence following at least 5 years of mass azithromycin distribution to discontinuation or continuation of 3 additional years of annual mass azithromycin distribution.

Condition Trachoma
Treatment Azithromycin
Clinical Study IdentifierNCT04185402
SponsorUniversity of California, San Francisco
Last Modified on20 August 2023


Yes No Not Sure

Inclusion Criteria

Provision of appropriate informed consent
Stated willingness to comply with all study procedures
Live in one of the 80 communities with up to 20% prevalence of TF selected for the trial

Exclusion Criteria

Does not consent to participation
Unwilling to comply with all study procedures
Does not live in one of the 80 communities with up to 20% prevalence of TF selected for the trial
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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