Ketamine Assisted Psychotherapy for Opioid Use Disorder

  • STATUS
    Recruiting
  • End date
    May 30, 2023
  • participants needed
    60
  • sponsor
    University of Utah
Updated on 31 May 2021

Summary

This pilot clinical trial aims to assess the preliminary efficacy of ketamine as an adjunct for a mindfulness-based intervention for opioid use disorder.

Description

The purpose of this study is to conduct a Stage 1 randomized controlled trial to test a potential optimization of the evidence-based Mindfulness-Oriented Recovery Enhancement (MORE) intervention for opioid use disorder (OUD). Here we will add Ketamine to MORE (MORE+KAP) and test the MORE+KAP intervention versus the standard MORE intervention in a sample of patients receiving medications for OUD (MOUD; e.g, buprenorphine). The primary aim to is evaluate the extent to which MORE+KAP improves OUD treatment relative to MORE. The secondary aim is to identify the psychobiological mediators of MORE+KAP.

Details
Condition Opioid Use Disorder
Treatment MORE+KAP, MORE, MORE
Clinical Study IdentifierNCT04892251
SponsorUniversity of Utah
Last Modified on31 May 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Diagnosis of Opioid Use Disorder
Receiving OUD treatment with a buprenorphine formulation

Exclusion Criteria

Previous experience with a mindfulness-based intervention program
Pregnancy
Any serious medical, mental, or cognitive issue that prevents successful participation in a mindfulness-based group treatment program
Prior use of ketamine other than as prescribed by a physician
Any of the following medical conditions
Blood Vessel Disease Heart Valve Disease Heart Failure Class 2 or Above Heart
Disease Pregnancy/Breastfeeding Arteriovenous Malformation History of
Intracranial Bleeding or Stroke History of Seizures Hypoxia defined by current
need for supplemental oxygen Liver Disease History of allergic reaction to
Ketamine Dementia (moderate-severe) History of Psychotic Disorder, Bipolar
Disorder, or Personality Disorder Dissociative Identity Disorder
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note