Deployment o the Multidisciplinary Prospective Cohort Imminent (IMMINeNT)

  • End date
    Jul 9, 2031
  • participants needed
  • sponsor
    University Hospital, Lille
Updated on 9 June 2022
disease or disorder


Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions.

Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite progress in this field, much remains to be done in clinical, therapeutic and fundamental research to address the efficacy, resistance and side-effects of treatment.

These similarities between IMIDs have led the FHU IMMINeNT to propose the creation of a prospective, multidisciplinary clinical-biological database (IMMINeNT cohort), associated to a biobank, of patients with IMIDs. The main objectives of this database will be to identify new prognostic and therapeutic biomarkers in order to develop new therapeutic targets and biomarkers, to identify prognostic factors and determinants related to the activity, severity and quality of life of patients with IMIDs as well as to the response and tolerance to treatment.

Condition Chronic Inflammatory Disease, Angioedema, Severe Asthma, Lupus, Atopic Dermatitis, Psoriatic Arthritis, Multiple Sclerosis, Systemic Sclerosis, Behçet Disease
Treatment Biobanking with genetic analysis, SF-12 questionnaire
Clinical Study IdentifierNCT04334031
SponsorUniversity Hospital, Lille
Last Modified on9 June 2022


Yes No Not Sure

Inclusion Criteria

Patient followed for their IMID in one of the departments of the Lille University Hospital participating in the study (dermatology, internal medicine, neurology, pneumology and rheumatology)
Social insured
Have the capacity to understand the study requirements, provide written informed consent, and comply with the study data collection procedures

Exclusion Criteria

Administrative reasons: inability to receive informed information, inability to participate in the entire study, lack of coverage by the social security system
Pregnant or breastfeeding woman
Persons deprived of liberty
Protected minors or adults
Persons who have refused or are incapable of giving informed consent
Persons in Emergency Situations
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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