Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part.

  • STATUS
    Recruiting
  • End date
    Sep 24, 2023
  • participants needed
    45
  • sponsor
    Dr. Stéphanie Delstanche
Updated on 24 May 2021
dysphagia
primary lateral sclerosis
riluzole

Summary

ActiSEP is a monocentric academic study. Patients with amyotrophic lateral sclerosis may be included on a voluntary basis. The investigators plan to include a group of approximately 45 patients with ALS.

The investigators have planned to assess patient every three months for a year. On each visit, participants will undergo a clinical examination with MRC sum score and Ashworth scores.

They will perform few tests ( 6-minutes walk test (6MWT), dynamometric measure, electromyography, Edinburgh Cognitive and Behavioural ALS Screen ) and will answer to some questionaires (dysphagia handicap scale, ALS-SFR-r).

After each visit, participants will wear Actimyo for one month daily.

Details
Condition Myelopathy, Amyotrophic Lateral Sclerosis (ALS), Amyotrophic Lateral Sclerosis, lou gehrig's disease, Spinal Cord Disorders
Treatment Actimyo°
Clinical Study IdentifierNCT04882904
SponsorDr. Stéphanie Delstanche
Last Modified on24 May 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Clinically defined or probable diagnosis of ALS according to El Escorial criteria revised with Awaji's electro-diagnostic algorithm
Over 18 years old
Signed informed consent
If patient on Riluzole, the dosage should be stable for 1 month and continued throughout the study period

Exclusion Criteria

Patients with excessive cognitive disorders, limiting the understanding of task or with apparent communication difficulties hindering data collection
Any other previous or present pathology having an impact on motor function
Recent surgery or trauma (less than 6 months) in the upper or lower limbs
Prior neurological, endocrine, infectious, allergic, or chronic or acute inflammatory pathology in the three weeks preceding inclusion
Patients participating in an interventional clinical trial
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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