tDCS in Post-Acute COVID-19 Patients With SARDs

  • End date
    Dec 24, 2022
  • participants needed
  • sponsor
    University of Sao Paulo
Updated on 19 June 2022
rheumatic diseases


Some patients develop "Post-acute COVID-19 syndrome," in which they experience persistent symptoms after recovering from the acute phase of COVID-19 infection. This syndrome may be more significant in patients with systemic autoimmune rheumatic diseases (SARDs) who have been suffering from several symptoms associated to SARDs, such as myalgia, fatigue, and general pains.

The transcranial direct current stimulation (tDCS) technique has been frequent, for example, to relieve fatigue and general pains in general population. However, to date, there are no studies evaluating this technique in ARD patients with post-acute COVID-19; therefore, the main objective of the opened study is to evaluate the safety and efficacy of the application of acute tDCS in ARD patients with post-acute COVID-19.


Currently, there are no studies evaluating the tDCS technique in ARD patients with post-acute COVID-19; therefore, the main objective of the present study is to evaluate the safety and efficacy of the application of acute tDCS in these specific patients.

Condition Rheumatic Diseases, Autoimmune Diseases
Treatment Transcranial Direct Current Stimulation
Clinical Study IdentifierNCT04890483
SponsorUniversity of Sao Paulo
Last Modified on19 June 2022


Yes No Not Sure

Inclusion Criteria

Patients with well-defined ARDs (rheumatoid arthritis, sclerosis systemic, Sjögren syndrome, spondyloarthritis, systemic lupus erythematosus, systemic vasculitis, and systemic autoimmune myopathies)
Fatigue or general pains

Exclusion Criteria

Neoplasia, using heart pacemarker, using visceral metalic clips, infections (HIV, HTLV-1, hepatitis), pregnance, previous historical of convulsions or epilepsies
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