Last updated on March 2019

Comparison of 2 Strategies of Adjustment of Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Acute Respiratory Distress Syndrome | Acute Lung Injury
  • Age: Between 18 - 100 Years
  • Gender: Male or Female
  • Other:
    Mechanical ventilation through an endotracheal tube
    Bilateral infiltrates consistent with pulmonary edema
    PaO2/FiO2 < 300 mmHg
    No clinical evidence of left atrial hypertension. If measured, pulmonary artery
    occlusion pressure < 18 mmHg
    Criteria 1, 2 et 3 jointly present for less than 48 hours
    Written informed consent obtained from the patient or surrogate

You may not be eligible for this study if the following are true:

  • Age < 18 years
    Expected duration of mechanical ventilation through an endotracheal tube < 48 hours
    Participation in other trials within the previous 30 days
    Increased intracranial pressure
    Severe chronic respiratory disease
    Morbid obesity (weight > 1kg/cm)
    Sickle cell disease
    Bone marrow transplant or chemotherapy-induced neutropenia
    Extended burns (> 30 % total body surface area)
    Severe chronic liver disease (Child-Pugh score C)

Recruitment Status: Closed

Brief Description Eligibility Contact Research Team

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