Analysis of Frailty Syndrome Within the Framework of the Innovation Fund Project PR P-GO (ANA-PR P-GO)

  • End date
    Nov 14, 2022
  • participants needed
  • sponsor
    Charite University, Berlin, Germany
Updated on 14 June 2021
Claudia Spies, MD
Primary Contact
Paul Gerhard Diakonie - Evangelisches Waldkrankenhaus Spandau (4.9 mi away) Contact
+23 other location


The patients included in PRP-GO and the corresponding comparison cohorts will be offered to participate in this complementary study in order to be able to carry out a detailed characterization and phenotyping of the frailty complex.


As part of the innovation fund project PRP-GO (EA1/225/19), a multimodal intervention is being conducted in patients with a frailty syndrome. However, the health care research project is limited to evaluating clinical issues only. In order to be able to research further pathophysiological, clinical, psychosocial and work-organizational connections, different groups of participants will be offered the participation in this scientific support program of PRP-GO.

The groups of participants in this accompanying program ANA-PRP-GO are:

  • Randomized study patients with a frailty syndrome of the intervention study PRP-GO (PG cohort)
  • Non-frail surgical control group (NFC cohort)
  • Non-operative control group (NO cohort)
  • Participants with health professions (GB cohort)

Additionally, relatives of the patients can be included.

Subprojects are included to reflect research questions of interest in sub groups:

  • Success of endoprosthetic implants (clinical outcome and gait pattern after total hip arthroplasty and total knee arthroplasty in frail patients)
  • Functional treatment outcome and health-related quality of life after elective spinal surgery in the PG cohort, in the NFC cohort, and in the NO cohort
  • Hemodynamic evaluation in patients of the PG and NFC cohort with preoperative abnormal cardiovascular function
  • Establishment of a German standard database for 14 CANTAB tests by CANTAB Connect technology
  • Aggregated evaluation of the cognitive data of different anesthesiological study cohorts to describe domain-specific changes in the perioperative course

Condition Frailty Syndrome
Treatment Prehabilitation- new form of care
Clinical Study IdentifierNCT04880824
SponsorCharite University, Berlin, Germany
Last Modified on14 June 2021


Yes No Not Sure

Inclusion Criteria

Age 70 years
No elective surgery planned
No surgery within 6 months prior to study enrollment
Exclusion criteria - See NFC cohort
GB cohort
Inclusion criterion
Doctor, nurse or therapist from the cooperation partners of PRAEP-GO who were involved in the project
Exclusion criterion
Language barrier
Inclusion criteria
Member of a patient in the PRP-GO cohort
Age 18 years
Exclusion criterion
Language barrier

Exclusion Criteria

Severe cardiac or pulmonary disease (NYHA IV, Gold IV)
Intracranial interventions
Moribund patients (palliative situation)
Patients with a neuropsychiatric clinical picture or severe hearing and / or visual acuity impairment (not compensated by visual or hearing aids), which limit the performance of the neurocognitive tests
Insufficient language skills
Participation in another interventional rehabilitation study or a study according to the German Drug Law or the medical Device Law that has not been approved by the study leader (Exception: parallel participation in adjuvant therapy study)
NO cohort
Clear my responses

How to participate?

Step 1 Connect with a site
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Preferred Language
Other Language
Please verify that you are not a bot.

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note