A Study of Intra-operative Imaging in Women With Ovarian Cancer

  • End date
    May 3, 2025
  • participants needed
  • sponsor
    Memorial Sloan Kettering Cancer Center
Updated on 14 July 2022
fallopian tube
peritoneal cancer
tumor debulking
cytoreductive surgery
cancer of the ovary
surgery for ovarian cancer


The purpose of this study is to find out whether using the PINPOINT imaging system intra-operatively can reduce the risk of anastomotic leaks and other complications after surgery for ovarian cancer, compared with standard intra-operative assessments alone. The PINPOINT endoscopic fluorescence imaging system uses a special camera and a fluorescent (glowing) dye that can evaluate the blood flow of the bowel in real-time. If there is an area that appears concerning, the surgeon can correct the problem during the procedure.

Condition Ovarian Cancer, Ovarian Carcinoma
Treatment Endoscopy, Intravenous Indocyanine Green/ICG injection, PINPOINT endoscopic fluorescence imaging system
Clinical Study IdentifierNCT04878094
SponsorMemorial Sloan Kettering Cancer Center
Last Modified on14 July 2022


Yes No Not Sure

Inclusion Criteria

Part 1 (pre-operative)
Diagnosed with primary or recurrent ovarian, fallopian tube, or primary peritoneal cancer
Scheduled to undergo debulking or cytoreductive surgery
Suspected need for a low anterior rectosigmoid resection at the time of a debulking procedure
Enrolled and consented before the operation
Part 2 (intra-operative)
Completed rectosigmoid resection
Surgeon plans to perform colorectal anastomosis

Exclusion Criteria

Part 1 (pre-operative)
Documented history of allergic reaction to ICG
Not approached for study enrollment before undergoing an unexpected low anterior rectosigmoid resection
Part 2 (intra-operative)
Did not undergo rectosigmoid resection intraoperatively
Surgical procedure with rectosigmoid resection for any other type of gynecologic malignancy
Patient requires permanent colostomy
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