Rehabilitation in Patients With Human Lymphotropic Virus Type I

  • End date
    Dec 30, 2022
  • participants needed
  • sponsor
    Universidade Metodista de Piracicaba
Updated on 14 May 2021


In our times, it is known that approximately 5% of patients seropositive for HTLV-1 may desengage a frame with several neurological disorders, which is called myelopathy associated with HTLV-1, characterized for gait, decreased dynamic balance and limitation of walking independence the use of walkers, crutches as in wheelchairs. This evolution of the disease is based, above all, on muscle changes, such as inflammation of the muscles, which contributes to the attenuation of muscle capacity . In addition, muscle changes caused by HTLV-1 also affect the respiratory muscles, causing a change in respiratory mechanics, which can impair alveolar ventilation and, therefore, the development of a restorative respiratory disorder, reducing total lung capacity. Therefore, it is perceived the importance of offering planned rehabilitation according to the global assessment of the health status of these patients, considering their influence on activities of daily living.The focus of this study is on the weekly respiratory muscle training, as assessed by mensuration maximal inspiratory pressure, showed significant results in improving lung capacity and in this way promoting the prevention of pulmonary complications. Therefore, the protocol proposed by the present study includes respiratory muscular training plus resistance exercise, assessing the impact on both the strength muscular respiratory to as peripheral muscles, through the palmar pressure test and consequent enhancement of quality life and functionality of these patients. Furthermore, it will be possible to contribute to the knowledge of society and the scientific community about this theme, which is still very small in the world literature.

Condition Tropical spastic paraplegia
Treatment Exercise, Inspiratory muscle trainning
Clinical Study IdentifierNCT04875403
SponsorUniversidade Metodista de Piracicaba
Last Modified on14 May 2021


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Inclusion Criteria

Seropositive carriers for HTLV-1 with PET

Exclusion Criteria

lung diseases
heart disease
arterial hypertension
cognitive impairments
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