A Washington University research study is currently enrolling participants with diagnosed primary immunodeficiency disorder (PID).

Updated on 11 May 2021


The purpose of the research study is to find out if the COVID – 19 vaccine can produce an immune response in patients with PID. The study will also look at genetic factors that determine response. 


Participants will complete up to 6 visits (4 visits are optional study visits). There will be blood draws at each study visit. Compensation is not provided. 

Study Contact Information:
Caitlin O’Shaughnessy

Condition Vaccines, Primary Immunodeficiency, Primary Immunodeficiency Disorders, COVID-19, Covid-19
Clinical Study IdentifierTX273274
Last Modified on11 May 2021


Yes No Not Sure

Inclusion Criteria

Participants must be 18 or older
Participants must have health care provider-documented PID (including CVID, hypogammaglobulinemia and specific antibody deficiency)
Participants must plan to receive the SARS-CoV-2 vaccination OR have recently received the SARS-CoV-2 vaccination within 28 days of the first visit
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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