Neurofeedback in Individuals With Substance Use Disorders

  • participants needed
  • sponsor
    Yale University
Updated on 4 October 2022
substance use
opioid use
opioid use disorder
methadone treatment
toxicology screen
urine screening


The aim of this study is to train individuals with opioid use disorder to control their brain activity in a way that has been associated with their symptoms. Participants in the experimental group will be given direct feedback regarding their brain activity while they are undergoing functional magnetic resonance imaging (fMRI) scanning, and will try to learn to control their brain activity during these feedback sessions. A separate group of participants will be given a control form of feedback that we do not believe can have clinical benefits. Our primary hypothesis is that the neurofeedback training will reduce opioid use and clinical features of opioid use disorder more than the control feedback.

Condition Opioid Use Disorder, Drug abuse, opioid-related disorders, Substance Abuse, Drug use, Opioid Dependence
Treatment control feedback, Experimental Feedback
Clinical Study IdentifierNCT04188288
SponsorYale University
Last Modified on4 October 2022

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