Evaluation of Left Ventricular Function by Speckle Tracking Echocardiography in Patient Hospitalised in Intensive Care Unit for Vaso-occlusive Crisis

  • End date
    Dec 1, 2023
  • participants needed
  • sponsor
    Bicetre Hospital
Updated on 26 January 2022
vaso-occlusive crisis


Vaso-occlusive crisis in Sickle cell disease might alter myocardial function through micro vascular obstruction. Evaluation of strain alteration using speckle tracking echocardiography is a non invasive technique that may allow us to observe such myocardial dysfunction. No such study has yet been conducted in patient hospitalised in intensive care unit. Our hypothesis is that strain alteration during vaso-occlusive crisis, if they do exist, can be correlated with other markers of myocardial injury such as troponin level or thoracic pain.

Condition Sickle Cell Disease
Treatment Evaluation of global longitudinal strain using routinely recorded echocardiography images
Clinical Study IdentifierNCT04864041
SponsorBicetre Hospital
Last Modified on26 January 2022


Yes No Not Sure

Inclusion Criteria

Hospitalisation in an intensive care unit for vaso-occlusive crisis

Exclusion Criteria

Individuals under guardianship
Unsufficient echogenicity
Thoracic pain prohibiting echocardiography assessment
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