Effects of Electrostimulation on Glycemic Control in Obesity

  • End date
    Jun 1, 2023
  • participants needed
  • sponsor
    Fondation Ildys
Updated on 1 May 2021


This study evaluate the effects of muscle electrostimulation (MES) on carbohydrate homeostasis in adult patients with obesity. Its aims are also to evaluate the tolerance of feasibilty and the tolerance of MES and the impact on basal metabolism ; muscle mass (maintenance, gain or loss) in a context of calorie restriction ; physical capacities ; adherence to the usual rehabilitation program ; eating behavior : quality of life.


Prevalence of adult obesity in general french population (15%) justifies the implementation of innovative care. Prescribing regular physical activity is one of the recommendations for managing obesity. However, patients find it difficult because of non-adapted offered activities; non-achievement concrete results despite the effort; difficulties to manage activities and to plan objective. Situation is seen as a failure and discourages patients. In addition, the obese patient may suffer from orthopedic disorders, cardiovascular contraindications, and the excessive weight in itself may force him to become sedentary. The recommendations on the practice of physical activity in the overall management of obesity are therefore not always applicable.

Muscle electrostimulation (MES) could therefore be an interesting additional tool in the management of obesity and particularly of glycemic control in obese patients suffering from type 2 diabetes.

Studies are still relatively few and present certain limits (small samples, short period of MES, very specific populations, few parameters evaluated, lack of consensus on the methods of MES, etc.). The results are nevertheless encouraging and call for the implementation of additional studies.

Investigators therefore propose a controlled, randomized, single-center study in a group of 60 adult patients suffering from severe or morbid obesity (BMI> = 35) in a 3-week rehabilitation stay.

The aims are to establish whether MES is a possible and interesting tool in the management of obesity, by checking the following hypotheses:

  • control of carbohydrate metabolism is better when a MES is implemented;
  • MES sessions improve patients' physical capacities and / or their tolerance to exercise;
  • MES improves the quality of life of patients;
  • MES improves patient adherence to the usual nutritional rehabilitation program;
  • MES sessions are well tolerated and the accepted intensity nevertheless guarantees sufficient muscle stimulation.

Condition Obesity Adult Onset
Treatment Muscle Electrostimulation
Clinical Study IdentifierNCT04643899
SponsorFondation Ildys
Last Modified on1 May 2021


Yes No Not Sure

Inclusion Criteria

men and women over 18 years old and under 70 years old
with severe or morbid obesity (BMI> = 35)
with or without bariatric surgery
able to understand and respect the protocol and its requirement
who signed the consent prior to any other procedure protocol

Exclusion Criteria

major patients under guardianship / curatorship / legal protection
pregnant patients
patients with epilepsy
with an implanted electronic/electrical device (cardiac pacemaker, intracardiac defibrillator, etc.)
with a baclofen pump
suffering from serious disorders of the arterial circulation in the lower limbs such as Peripheral Arterial Obstructive Disease (PAOD)
suffering from abdominal or inguinal hernia
suffering from cardiac arrhythmia
suffering from skin lesions and/or infections foci on one or more areas where the electrodes are placed
suffering from sensory disorders in the areas of stimulation
patients unable to complete the entire program
Clear my responses

How to participate?

Step 1 Connect with a site
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Preferred Language
Other Language
Please verify that you are not a bot.

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note