Assessing Effects of Heparin Priming and Pass Number on Tissue Quality of Fine Needle Biopsies

  • STATUS
    Recruiting
  • End date
    Aug 28, 2024
  • participants needed
    100
  • sponsor
    University of Michigan
Updated on 28 April 2022

Summary

This is a randomized study that will enroll patients scheduled for an endoscopic biopsy of a pancreas lesion to be in the heparin or saline group during the procedure.

The purpose of this study is to examine the effect of blood contamination, heparin priming of the fine needle biopsies, and pass number on tumor tissue quality in fine needle biopsies.

The hypothesis for this study is that fine needle biopsy tissue quality of pancreatic masses decreases with increasing pass number due to blood contamination; this blood contamination can be ameliorated with priming of the needle with an anticoagulant such as heparin.

Details
Condition Pancreas, Mass Lesion
Treatment Saline, Heparin will be used for needle priming (BD PosiFlush™ Pre-Filled Heparin Lock Flush Syringe)
Clinical Study IdentifierNCT04764396
SponsorUniversity of Michigan
Last Modified on28 April 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

patients identified as having a possible solid lesion in their pancreas on radiographic imaging
scheduled for endoscopic fine needle biopsy (FNB) for clinical purposes

Exclusion Criteria

known history of coagulopathy
history of heparin allergy
patients with evidence of vascular tumors on imaging
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