Comparison of Non-invasive Methods of Lung Ventilation in Patients With Respiratory Failure After Cardiac Surgery

  • STATUS
    Recruiting
  • days left to enroll
    31
  • participants needed
    90
  • sponsor
    Petrovsky National Research Centre of Surgery
Updated on 5 May 2022
pneumonia
FIO2
pao2
non-invasive ventilation
assisted ventilation
Accepts healthy volunteers

Summary

Comparison of the effectiveness of three methods of non-invasive ventilation in patients with mild and moderate respiratory failure in the early postoperative period after cardiac surgery

Description

The study includes the comparison of the three methods of non-invasive ventilation: non-invasive mask ventilation, high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) and non-invasive ventilation with a helmet in patients with mild and moderate respiratory failure in the early postoperative period after cardiac surgery. It assumes 90 randomized patients:30 patients in three study groups male and female aged 30 to 60 years of age inclusive, with mild or moderate respiratory failure.The study will be randomized, single-center, prospective.

Details
Condition Respiratory Failure
Treatment Using of non-invasive mask ventilation, high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) and non-invasive ventilation with a helmet
Clinical Study IdentifierNCT04787666
SponsorPetrovsky National Research Centre of Surgery
Last Modified on5 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Age from 30 years to 60 years inclusive
Decreased oxygenation function of the lungs (SpO2 less than 90%, PaO2/FiO2 less than 300, BH less than 25 per minute)
By data CT/x-ray examination of hypoventilation zones (pneumonia, atelectasis)
Consent the patient to participate in this study

Exclusion Criteria

Tracheal intubation, absence of independent breathing
Unstable hemodynamics or hemodynamically significant rhythm disturbances
Acute violation of the cerebral blood supply
Shocks of various etiologies
Impossibility provide respiratory protection , high risk of aspiration
Lack of productive contact with the patient
Patient's refusal to participate in this study
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