Elements Vital to Treat Obesity Study (EVO)

  • STATUS
    Recruiting
  • End date
    Jun 18, 2025
  • participants needed
    524
  • sponsor
    Northwestern University
Updated on 18 May 2022
diabetes
self monitoring
Accepts healthy volunteers

Summary

The overall objective of this study is to evaluate the first rigorously optimized, remotely delivered treatment for obesity against the current gold standard treatment in a head-to-head randomized controlled trial. The investigators will be comparing the previously developed and optimized behavioral weight loss intervention (APP) to the Diabetes Prevention Program (DPP), to evaluate program weight-loss success and cost-effectiveness.

Description

The proposed study seeks to determine if the APP program is an effective, resource-sensitive strategy to manage weight for obesity, as compared to the DPP program. During the 24-week active intervention phase, participants will be randomized to one of two treatments: 1) APP, wherein participants receive calorie, fat, and physical activity goals via a Smartphone application for self-monitoring, online educational readings, and biweekly sessions with a Health Promotionist; or 2) DPP, wherein participants are guided to self-monitor their physical activity, food intake, and weight via a participant log, and are guided through 16 sessions by a Health Promotionist. Assessments to track progress will occur remotely at the 3-month, 6-month, and 12-month time points of the program.

Details
Condition Obesity
Treatment Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP)
Clinical Study IdentifierNCT04708769
SponsorNorthwestern University
Last Modified on18 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

BMI 30-45
Weight stable
Own a Smartphone and be willing to install our Smartphone app
Willing to conduct video conference calls with study staff

Exclusion Criteria

Enrolled in any formal weight loss program
Taking anti-obesity medications
Not taking medications that may cause weight gain
Unstable medical conditions
Diabetes requiring insulin supplementation
Crohn's Disease
Diagnosis of obstructive sleep apnea requiring intervention (i.e., CPAP)
Assistive devices for mobility
Hospitalizations for a psychiatric disorder within the past 5 years
Cardiovascular disease symptoms while performing moderate intensity exercise
Pregnancy, trying to get pregnant, or lactating
Bulimia or binge eating disorder
Reports of active suicidal ideation
Current substance abuse or dependence besides nicotine dependence
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note