Does Low Dose of Dexamethasone Enhance Analgesic Quality of Caudal Analgesia in Children Undergoing Orchiopexy?

  • End date
    Mar 24, 2023
  • participants needed
  • sponsor
    Yonsei University
Updated on 22 April 2021


Caudal block is one of the most effective modalities to reduce pain both during and after the surgery involving areas under the umbilicus. According to previous research, 0.5mg/kg-1.5mg/kg dexamethasone is known to enhance the analgesic quality of caudal block in children. Despite the fact that this high dose of dexamethasone is used to treat airway edema in actual practice and no adverse side effect related to dosage has been reported, it is 3 to 15 times higher than the daily antiemetic dose of dexamethasone that is used in standard care of anesthesia. Therefore, our study aims to assess the effect of the more practical, antiemetic dose of dexamethasone (0.15mg/kg) as an adjuvant to enhance the quality of caudal block through a non-inferiority trial.

Condition Patients With Cryptorchism Who Are Planning to Undergo Orchiopexy
Treatment High dose dexamethasone, Low dose dexamethasone
Clinical Study IdentifierNCT04841018
SponsorYonsei University
Last Modified on22 April 2021


Yes No Not Sure

Inclusion Criteria

Ages from 6 months old to 6 years old
Body weight Less than or equal to 16.7kg
American Society of Anesthesiologists (ASA) classification I or II
Patients receiving orchiopexy under general anesthesia

Exclusion Criteria

Patients with uncorrected cardiac anomalies
Patients with vertebral anomalies
Diagnosis of diabetes mellitus
Diagnosis of adrenal disease
Currently on steroid
Body temperature above 37.5'C preoperatively
Allergy to dexamethasone
Laparoscopic surgery
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