RHYTHMIA vs CARTO in Redo Ablation Procedures for Atrial Fibrillation (MAP-AF)

  • End date
    Jul 1, 2024
  • participants needed
  • sponsor
    The Cleveland Clinic
Updated on 10 April 2022


The MAP-AF study will compare RHYTHMIA vs CARTO in redo ablation of paroxysmal AF with assessment of both acute procedural profiles and clinical outcomes.


Pulmonary venous conduction recovery is found in most patients undergoing redo ablation procedures for atrial fibrillation (AF). Identifying gaps in prior ablation lines is essential to achieve successful outcomes. High density mapping systems have been proposed to allow the identification of such gaps with speed and accuracy.

The MAP-AF study will compare RHYTHMIA vs CARTO in redo ablation of paroxysmal AF with assessment of both acute procedural profiles and clinical outcomes.

Condition Paroxysmal Atrial Fibrillation
Clinical Study IdentifierNCT04835844
SponsorThe Cleveland Clinic
Last Modified on10 April 2022


Yes No Not Sure

Inclusion Criteria

Adult patients (18-90 years of age) undergoing redo ablation procedures for paroxysmal AF regardless of the systems or energy sources used during the pre-study ablation procedure(s)
Paroxysmal AF: defined as AF terminating within 7 days of onset either spontaneously or with electrical or medical cardioversion

Exclusion Criteria

Persistent AF
Prior cardiac surgery
Patients with only AFL or AT as the documented recurrent arrhythmia after the pre-study AF ablation(s)
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