An Ultrasound Imaging Technique to Measure Tumors in People With Pancreatic Ductal Adenocarcinoma (PDAC) or Gastrointestinal (GI) Adenocarcinoma

  • End date
    Apr 6, 2023
  • participants needed
  • sponsor
    Memorial Sloan Kettering Cancer Center
Updated on 29 May 2022
ct scan
pancreatic adenocarcinoma
pancreatic ductal adenocarcinoma
breast ductal carcinoma


The purpose of this study is to see if ultrasound images that are analyzed by a special computer program can be used to measure the size of PDAC tumors in the liver as accurately as CT scans that involve contrast material (also called contrast-enhanced CT scans). All participants in this study will have pancreatic ductal adenocarcinoma (PDAC) that has spread (metastasized) to the liver, and all participants will be scheduled for a routine CT scan that will measure their cancer.

Condition Pancreas Cancer, Gastrointestinal Adenocarcinoma
Treatment ultrasound
Clinical Study IdentifierNCT04837833
SponsorMemorial Sloan Kettering Cancer Center
Last Modified on29 May 2022


Yes No Not Sure

Inclusion Criteria

Male and female patients, 18 years of age or older
Confirmed diagnosis of PDAC or GI tract adenocarcinoma metastatic to liver
Scheduled for imaging with contrast enhanced CT

Exclusion Criteria

Inability to tolerate intravenous contrast medium
All liver metastases ≤ 10 mm in maximal diameter on the contrast enhanced CT used for comparison to the planned research ultrasound
Multiple confluent liver metastases or tumor burden > 50% of the liver as estimated by a radiologist
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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