The Safety of Intravenous Tranexamic Acid in Patients Undergoing Supratentorial Meningiomas Resection

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    Beijing Tiantan Hospital
Updated on 29 October 2021
tranexamic acid


Growing evidence of Tranexamic Acid (TXA) being used to reduce blood loss and blood transfusions in various guidelines. However, the adverse effects of TXA especially seizure has always been a problem of concern, especially in neurosurgery. Therefore, this study aims to provide a scientific evidence for the safety of TXA in supratentorial meningiomas resection patients.

Condition fits, fitting, seizures, convulsions, Meningiomas, Seizure, Meningioma
Treatment 0.9% saline, Tranexamic Acid
Clinical Study IdentifierNCT04595786
SponsorBeijing Tiantan Hospital
Last Modified on29 October 2021


Yes No Not Sure

Inclusion Criteria

) age 18-80 years
) American Society of Anesthesiologist (ASA) classification score I~III

Exclusion Criteria

) allergic to tranexamic acid
) preoperative seizures
) history of thrombotic disease
) chronic kidney disease
) breastfeeding or pregnancy
) refuse to participate in the study
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