Direct Comparison of Ga-68-DOTATATE and Ga-68-DOTATOC

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  • sponsor
    Weill Medical College of Cornell University
Updated on 19 April 2022


The goal of this study is to propose the first direct comparison of Ga-68-DOTATATE PET and Ga-68-DOTATOC PET in patients with meningioma.


The investigator is proposing a direct comparison of Ga-68-DOTATATE and -DOTATOC in a pilot cohort of patients with meningioma, and hypothesize non-inferiority of DOTATOC. This pilot study will form the basis for a subsequent prospective clinical trial and will allow us to optimize our existing imaging protocols, while developing a more cost-effective protocol.

Primary Objectives:

  • Optimize the Ga-68-DOTATATE and -DOTATOC PET protocol.
  • Compare Ga-68-DOTATATE and -DOTATOC PET in patients with meningioma.

Secondary Objectives

• Correlate Ga-68-DOTATATE and -DOTATOC PET with clinical and pathological characteristics

Condition Meningioma
Treatment Ga-68- DOTATATE, Ga-68-DOTATOC
Clinical Study IdentifierNCT04298541
SponsorWeill Medical College of Cornell University
Last Modified on19 April 2022


Yes No Not Sure

Inclusion Criteria

Adult patients with clinically suspected meningioma
Patients planned for surgery - undergoing preoperative workup
No contraindications to either radiotracer

Exclusion Criteria

Age less than 18 years
Inability to lay on the scanner table for the required period of time, e.g., due to bone pain or claustrophobia
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