Safety and Pharmacokinetics of the Combination Broadly Neutralizing Antibodies, 3BNC117-LS-J and 10-1074-LS-J, in Healthy American and African Adults

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    Recruiting
Updated on 6 April 2021

Summary

Researchers at The Rockefeller University are testing the safety of two broadly neutralizing antibodies (bNAbs) that can bind to HIV and block the virus from entering blood cells; thereby protecting people from becoming infected with HIV.

Description

In this study, we will test two experimental study products given either separately or together to see if they are safe, and to understand how long they last in the human blood. We hope to learn if there are side effects after receiving the study product(s), and how severe those side effects will be.

The two study products being tested are called 3BNC117-LS-J and 10-1074-LS-J. These two products which were discovered in patients with HIV are human antibodies against HIV that have been made in a laboratory. HIV is the virus that causes acquired immunodeficiency syndrome (AIDS). We are hoping that one day these antibodies can be used to prevent or treat HIV infection. 

Details
Condition *Healthy Patient Studies, *Healthy Volunteers
Clinical Study IdentifierTX270576
Last Modified on6 April 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Between 18 and 45 years of age
In good overall health
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