Clinical Efficacy of Erythropheresis in High Altitude Polycythemia

  • End date
    Oct 1, 2024
  • participants needed
  • sponsor
    Third Military Medical University
Updated on 11 May 2022


The clinical study is aimed to explore the efficacy and safety of erythropheresis in high altitude polycythemia.


The clinical study is aimed to explore the efficacy and safety of erythropheresis in high altitude polycythemia. People reside in highland diagnosed as high-altitude polycythemia were included and randomly divided into two groups. In one group, routine therapy including oxygen inspiration would be performed, while in another erythropheresis would be added. Symptom relief, blood oxygenation, and 6-minute walk test would be assessed and compared in the above two groups.

Condition High Altitude Polycythemia
Treatment Erythropheresis
Clinical Study IdentifierNCT04557995
SponsorThird Military Medical University
Last Modified on11 May 2022


Yes No Not Sure

Inclusion Criteria

>=18 years old;2.High altitude polycythemia; 3.Han nationality who have been in highland for over 12 months; 4. No other complications indicated by general examinations such as chest X-ray, electrocardiogram; 5. patients who are informed and informed consent form are acquired

Exclusion Criteria

Hypoxemia caused by other respiratory or cardiac diseases or polycythemia vera; 2. Acute or subacute mountain sickness ; 3. Acute or chronic infections and medication history ; 4. Psychiatric disorders or severe neurosis; 5. Malignant myeloproliferative disease; 6. Any contraindications to erythropheresis
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