GEN3014 Safety Trial in Relapsed or Refractory Hematologic Malignancies

  • End date
    Nov 11, 2023
  • participants needed
  • sponsor
Updated on 11 September 2021


This trial is an open-label, safety trial of GEN3014 (HexaBody-CD38). The trial consists of two parts: a dose escalation part phase 1, first-in-human (FIH), and an expansion part phase 2a.


The purpose of the escalation part of the trial is to determine the maximum tolerated dose (MTD) and the recommended phase 2 dose (RP2D), as well as to establish the safety profile of GEN3014 (HexaBody-CD38) in Relapsed or Refractory Multiple Myeloma and Other Hematologic Malignancies

Condition Lymphoproliferative Disorder, Multiple Myeloma, Lymphoproliferative disorders, multiple myeloma (mm)
Treatment GEN3014 (HexaBody®-CD38)
Clinical Study IdentifierNCT04824794
Last Modified on11 September 2021


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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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