A Phase 1b/2 Study of BMS-986158 Monotherapy and in Combination With Either Ruxolitinib or Fedratinib in Participants With DIPSS-Intermediate or High Risk Myelofibrosis
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- STATUS
- Recruiting
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- End date
- Apr 26, 2027
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- participants needed
- 192
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- sponsor
- Bristol-Myers Squibb
Summary
The purpose of this study is to assess the safety, tolerability, and efficacy of BMS-986158 alone and in combination with either Ruxolitinib or Fedratinib in participants with Dynamic International Prognostic Scoring System (DIPSS)-intermediate or high risk blood cancer. Part 1 consists of BMS-986158 in combination with either Ruxolitinib or Fedratinib and Part 2 consists of BMS-986158 in combination with either Ruxolitinib or Fedratinib and BMS-986158 alone.
Details
| Condition | Myelofibrosis |
|---|---|
| Treatment | Ruxolitinib, BMS-986158, FEDRATINIB |
| Clinical Study Identifier | NCT04817007 |
| Sponsor | Bristol-Myers Squibb |
| Last Modified on | 23 October 2022 |
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