Knotless Suture in Revision Total Joint Arthroplasty

  • End date
    Feb 1, 2023
  • participants needed
  • sponsor
    NYU Langone Health
Updated on 25 March 2022


Barbed suture has been demonstrated to be safe in primary hip and knee surgery and retrospective data suggests barbed suture represents no increased complications in the revision setting. Barbed suture may represent a faster, more effective way to perform revision arthroplasty closures. There are no Level I studies comparing traditional and barbed suture closure. The purpose of this study is to assess the surgical complexities of closures using closure time without sacrificing cosmesis or wound complications between the traditional closure and barbed closure.

Condition Arthroplasty
Treatment Conventional Closure: Knee, Barbed suture closure: Knee, Conventional Closure: Hip, Barbed suture closure: Hip
Clinical Study IdentifierNCT04403919
SponsorNYU Langone Health
Last Modified on25 March 2022


Yes No Not Sure

Inclusion Criteria

Patients ≥ 18 years of age
Surgical candidates undergoing revision total knee or total hip arthroplasty for one of the following indications second stage of two stage reimplantation for infection, mechanical loosening, instability, polyethylene wear, stiffness, or periprosthetic fracture

Exclusion Criteria

Patient is ≤ 18 years of age
Patient is unable to provide written consent
Patient has active infections in the operative leg/joint
Known Allergy to Suture material
Underlying Dermatological diseases affecting surgical site including dermatitis, eczema, or psoriasis; connective tissue or vascular disorders or diseases that would adversely affect wound healing; metastatic cancer; renal insufficiency (dialysis); steroid dependence; malnourishment; and other disease processes resulting in an immunocompromised state. Diabetes, smoking and obesity will be allowed as they are frequent comorbidities in our revision joint population
Anterior total hip replacement
Stage 1 of two stage revision for infection
Closure performed by plastic surgeon, including flap coverage
Vulnerable populations will not be enrolled in this study
Withdrawal Criteria
Failure to attend regularly scheduled follow up appointments
Deviation from closure protocol
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