Quality of Life After Hysterectomy (AdenoQOL)

  • End date
    Dec 6, 2030
  • participants needed
  • sponsor
    Oslo University Hospital
Updated on 6 May 2022
pelvic pain


Adenomyosis is a disease where ectopic endometrial-like glands affect the muscular wall of the uterus. About 70% of women affected by adenomyosis suffer from dysmenorrhea and menorrhagia. A levonorgestrel-releasing intrauterine device (LNG-IUD) is the first-choice treatment of adenomyosis, but is not always sufficiently effective in all women. Those women often end up removing the uterus (hysterectomy).

Hysterectomy is clinically regarded to be an efficient and final treatment of adenomyosis, but pelvic pain may also prevail after removal of the uterus. This study aimes to investigate the short - and long-term impact of hysterectomy on quality of life (QOL) and sexual function in women with adenomyosis, and further to evaluate if there is any difference compared to women that are removing their uterus due to other benign gynecological conditions.

Condition Adenomyosis, Quality of Life
Treatment hysterectomy
Clinical Study IdentifierNCT04791033
SponsorOslo University Hospital
Last Modified on6 May 2022


Yes No Not Sure

Inclusion Criteria

Premenopausal status defined by having had menstruation within the last 12 months, or age < 50 years if amenorrhea due to hormonal treatment
Hysterectomy planned due to a benign condition
Able to communicate in Norwegian or English
Electronic consent given

Exclusion Criteria

Age < 18 years, postmenopausal status or no menstrual bleeding for the last 12 months
Hysterectomy as part of female-to-male transition
Pelvic organ prolapse as an indication for hysterectomy
Gynecological cancer suspected at the time of inclusion
Not able to communicate in Norwegian or English
Clear my responses

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