Association of Temperature of Extremities and Necrotizing Enterocolitis(NEC)

  • STATUS
    Recruiting
  • End date
    Dec 31, 2024
  • participants needed
    200
  • sponsor
    Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Updated on 24 October 2022

Summary

Bloody stool and necrotizing enterocolitis(NEC) is two main focus in non-neonatal intensive care unit ward and usually lead to longed duration of hospitalization.

Neutral temperature is a environmental temperature where the infant's body temperature is normal under resting state, and the changes of body temperature and skin temperature are less than 0.2-0.3 centigrade. According the definition, a suggested temperature range is set. For example, if an infant's body weight is more than 2500 gram, the initial set of environmental temperature is 31.3 centigrade with a range of 29.8-32.8 centigrade.

low environmental temperature is a risk factor for Bloody stool and NEC. Therefore, how to set the optimal environmental temperature is a challenge.

Description

After birth, newborns must adapt to their relatively cold environment by the metabolic production of heat because they are not able to generate an adequate shivering response. Under the condition, environment temperature should be given to protect an infant from cold stress and cold injury, even NEC.

Therefore, the setting of the optimal environment temperature is a key focus in neonatal ward. Here, the investigators suggest a hypothesis that environment temperature should be set to keep warmth of extremities temperature and infant's body temperature is between 36.7-37.3 centigrade.

In the present study, the investigators will test the hypothesis.

Details
Condition Neutral Temperature, Bloody Stool, Necrotizing Enterocolitis
Treatment normal body temperature and warm extremities, normal body temperature and cold extremities
Clinical Study IdentifierNCT04801537
SponsorDaping Hospital and the Research Institute of Surgery of the Third Military Medical University
Last Modified on24 October 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

body weight >2500 grams and/or gestational age >35 weeks
an infant is diagnosed with hyperbilirubinemia and/or pneumonia without need for oxygen inhalation

Exclusion Criteria

congenital deformities
refusal of parents' consent
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