The Effectiveness of Transcranial Magnetic Stimulation of Supplementary Motor Area (SMA) in Patients With Bladder Hypersensitivity and Bladder Pain

  • participants needed
  • sponsor
    Joint-Stock Company North-West Center for Evidence-Based Medicine, Russian Federation
Updated on 27 January 2022


The main hypothesis of this study is that transcranial magnetic neuromodulation can correct the symptoms of hypersensitivity and bladder pain. The investigators assume that under the influence of transcranial magnetic stimulation, both the subjective state of patients assessed by standardized questionnaires and the objective parameters assessed by invasive and non-invasive urodynamic studies will be improved. In this study, two protocols for magnetic stimulation of the supplementary motor area (SMA) will be compared with each other and with placebo. The investigators expect to determine the dependence of the therapeutic effect on the applied stimulation protocol.


The aim of the study is to test the hypothesis that the use of the magnetic stimulation method SMA in patients with symptoms of bladder hypersensitivity and bladder pain will help to reduce the clinical and urodynamic signs of these pathological conditions.

Condition Bladder Hypersensitivity
Treatment transcranial magnetic stimulation
Clinical Study IdentifierNCT04721210
SponsorJoint-Stock Company North-West Center for Evidence-Based Medicine, Russian Federation
Last Modified on27 January 2022

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